Comments on: Is the cystic fibrosis is one of the example of the chronic obstructive pulmonary disease? http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html Thu, 09 Sep 2010 11:49:50 +0000 http://wordpress.org/?v=2.8 hourly 1 By: Mary H http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html/comment-page-1#comment-2096 Mary H Sun, 02 Aug 2009 07:06:11 +0000 http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html#comment-2096 Cystic Fibrosis (CF) can indeed lead to a form of COPD due to the development of bronchiectasis that has been caused by repeated lung infections. As for the average life expectancy in Canada it's now 37, however, I know of many adults who are alive and doing fairly well despite their CF in their 30's, 40's, 50's, and even a few in their 60's and one man in his late 70's. Hence, CF is can no longer be considered chiefly as a paediatric disease. In my own case, I have severe lung disease due to bronchiectasis associated with my CF. However, I'm amongst the 10-15% of persons with CF who are pancreatic sufficient. Meaning that I do not need to take enzymes with my meals. My CF is severe due to recurrent lung infections. In fact, my only chance of having a somewhat more normal life will be if a double lung transplant happens in the near future. In my case, severe sinus infections, CF-related arthritis, osteopenia, a precursor to osteoporosis and milder digestive problems due to reflux are also factors due to my CF. I've been chronically-ill since childhood. In and out of hospital many times, requiring home IV antibiotics for years, etc. My CF was officially diagnosed at age 27 with the nasal potential difference (NPD) test at The Hospital for Sick Children (otherwise known as Sick Kids) in Toronto, Ontario, The NPD test can help make a diagnosis of CF that's been missed by sweat testing and by genetics. The most comprehensive genetics testing for CF is offered in the US by Ambry, and also by Johns Hopkins Hospital, In Canada Sick Kids supposedly tests for many mutations. Currently, 1400+ "known" mutations have been identified thus far and researchers continue to find more associated with CF. Hope this answer is helpful. Cystic Fibrosis (CF) can indeed lead to a form of COPD due to the development of bronchiectasis that has been caused by repeated lung infections. As for the average life expectancy in Canada it’s now 37, however, I know of many adults who are alive and doing fairly well despite their CF in their 30’s, 40’s, 50’s, and even a few in their 60’s and one man in his late 70’s. Hence, CF is can no longer be considered chiefly as a paediatric disease. In my own case, I have severe lung disease due to bronchiectasis associated with my CF. However, I’m amongst the 10-15% of persons with CF who are pancreatic sufficient. Meaning that I do not need to take enzymes with my meals. My CF is severe due to recurrent lung infections. In fact, my only chance of having a somewhat more normal life will be if a double lung transplant happens in the near future. In my case, severe sinus infections, CF-related arthritis, osteopenia, a precursor to osteoporosis and milder digestive problems due to reflux are also factors due to my CF. I’ve been chronically-ill since childhood. In and out of hospital many times, requiring home IV antibiotics for years, etc. My CF was officially diagnosed at age 27 with the nasal potential difference (NPD) test at The Hospital for Sick Children (otherwise known as Sick Kids) in Toronto, Ontario, The NPD test can help make a diagnosis of CF that’s been missed by sweat testing and by genetics. The most comprehensive genetics testing for CF is offered in the US by Ambry, and also by Johns Hopkins Hospital, In Canada Sick Kids supposedly tests for many mutations. Currently, 1400+ "known" mutations have been identified thus far and researchers continue to find more associated with CF.

Hope this answer is helpful.

]]> By: matador89 http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html/comment-page-1#comment-2097 matador89 Sun, 02 Aug 2009 07:06:11 +0000 http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html#comment-2097 Cystic Fibrosis is a condition with which some babies are born. In fact, it is present from the moment of conception, that is, from the instant the father's sperm fertilises the mother's egg. It is not caused by any previous illness suffered by one of the parents or by anything that happened during the mother's pregnancy. It is non-contagious and affects a number of organs of the body. Cystic Fibrosis is an inherited disorder. A baby can only be born with the disease if both parents carry the abnormal gene. This is what is known as an 'autosomal recessive' inheritance. Normally the mucus in our bodies is thin and slippery and works as a lubricant. In CF, however, the mucus becomes very thick and sticky, blocking the tiny tubes and ducts of various organs. In approximately 90 per cent of patients the ducts in the pancreas are blocked, and so digestive enzymes produced by the pancreas are unable to flow into the digestive tract. Mucus may also block the tiny bronchial tubes in the lungs causing shortness of breath and a chronic cough. Recurrent respiratory infections, and malabsorption due to pancreatic insufficiency are the major clinical manifestations of the condition. When the condition was first discovered, it was thought that the main effect was on the pancreas, an organ in the body which produces digestive juices. The pancreas in children with Cystic Fibrosis contains cysts and increased fibrous tissue, hence the term Cystic Fibrosis of the pancreas. It is now realised that the effects on the pancreas are only one aspect of the condition which is commonly termed Cystic Fibrosis or CF. I add a link with details of this subject http://www.cftrust.org.uk/ aboutcf/whatiscf/ Hope this helps matador 89 Cystic Fibrosis is a condition with which some babies are born. In fact, it is present from the moment of conception, that is, from the instant the father’s sperm fertilises the mother’s egg. It is not caused by any previous illness suffered by one of the parents or by anything that happened during the mother’s pregnancy. It is non-contagious and affects a number of organs of the body. Cystic Fibrosis is an inherited disorder. A baby can only be born with the disease if both parents carry the abnormal gene. This is what is known as an ‘autosomal recessive’ inheritance. Normally the mucus in our bodies is thin and slippery and works as a lubricant. In CF, however, the mucus becomes very thick and sticky, blocking the tiny tubes and ducts of various organs. In approximately 90 per cent of patients the ducts in the pancreas are blocked, and so digestive enzymes produced by the pancreas are unable to flow into the digestive tract. Mucus may also block the tiny bronchial tubes in the lungs causing shortness of breath and a chronic cough. Recurrent respiratory infections, and malabsorption due to pancreatic insufficiency are the major clinical manifestations of the condition. When the condition was first discovered, it was thought that the main effect was on the pancreas, an organ in the body which produces digestive juices. The pancreas in children with Cystic Fibrosis contains cysts and increased fibrous tissue, hence the term Cystic Fibrosis of the pancreas. It is now realised that the effects on the pancreas are only one aspect of the condition which is commonly termed Cystic Fibrosis or CF.
I add a link with details of this subject

http://www.cftrust.org.uk/
aboutcf/whatiscf/

Hope this helps
matador 89

]]> By: bob http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html/comment-page-1#comment-2098 bob Sun, 02 Aug 2009 07:06:11 +0000 http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html#comment-2098 yes as it affects the lungs Cystic fibrosis (CF), also called mucoviscidosis, is a hereditary disease that mainly affects the lungs and digestive system, causing progressive disability and early death. Formerly known as cystic fibrosis of the pancreas, this entity has increasingly been labeled simply "cystic fibrosis".Average life expectancy is around 31 years, although improvements in treatments mean a baby born today could expect to live for longer.". Difficulty breathing and insufficient enzyme production in the pancreas are the most common symptoms. Thick mucous production as well as a less competent immune system results in frequent lung infections, which are treated, though not always cured, by oral and intravenous antibiotics and other medications. A multitude of other symptoms, including sinus infections, poor growth, diarrhea, and potential infertility (mostly in males, due to the condition Congenital bilateral absence of the vas deferens) result from the effects of CF on other parts of the body. Often, symptoms of CF appear in infancy and childhood; these include meconium ileus, failure to thrive, and recurrent lung infections. yes as it affects the lungs

Cystic fibrosis (CF), also called mucoviscidosis, is a hereditary disease that mainly affects the lungs and digestive system, causing progressive disability and early death. Formerly known as cystic fibrosis of the pancreas, this entity has increasingly been labeled simply "cystic fibrosis".Average life expectancy is around 31 years, although improvements in treatments mean a baby born today could expect to live for longer.".

Difficulty breathing and insufficient enzyme production in the pancreas are the most common symptoms. Thick mucous production as well as a less competent immune system results in frequent lung infections, which are treated, though not always cured, by oral and intravenous antibiotics and other medications. A multitude of other symptoms, including sinus infections, poor growth, diarrhea, and potential infertility (mostly in males, due to the condition Congenital bilateral absence of the vas deferens) result from the effects of CF on other parts of the body. Often, symptoms of CF appear in infancy and childhood; these include meconium ileus, failure to thrive, and recurrent lung infections.

]]> By: Chipslittlepunk http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html/comment-page-1#comment-2099 Chipslittlepunk Sun, 02 Aug 2009 07:06:11 +0000 http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html#comment-2099 No. Cystic fibrosis is a genetic disease that attacks the patient's lungs and digestive system. It causes secretions from these systems to be extremely thick almost the consistancy of rubber cement. The secretions are so thick that they "stick" in the patients lungs and digestive tract and therefore make the patient vulnerable to infections. COPD or chronic obstructive pulmonary disease is a broad term that encompasses disorders like emphysema and chronic bronchitis. This disease is not genentic but caused by the patient usually a smoker or someone who was exposed to inhalation hazards over a long period of time. Hazards include smoking, asbestos, coal dust, and prolonged exposure to strong cleaning agents to name a few. So in essence thought cystic fibrosis is genetic and COPD is a disease brought on by environment. No. Cystic fibrosis is a genetic disease that attacks the patient’s lungs and digestive system. It causes secretions from these systems to be extremely thick almost the consistancy of rubber cement. The secretions are so thick that they "stick" in the patients lungs and digestive tract and therefore make the patient vulnerable to infections.

COPD or chronic obstructive pulmonary disease is a broad term that encompasses disorders like emphysema and chronic bronchitis. This disease is not genentic but caused by the patient usually a smoker or someone who was exposed to inhalation hazards over a long period of time. Hazards include smoking, asbestos, coal dust, and prolonged exposure to strong cleaning agents to name a few.

So in essence thought cystic fibrosis is genetic and COPD is a disease brought on by environment.

]]> By: VeeBee http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html/comment-page-1#comment-2100 VeeBee Sun, 02 Aug 2009 07:06:11 +0000 http://copdlungdisease.com/is-the-cystic-fibrosis-is-one-of-the-example-of-the-chronic-obstructive-pulmonary-disease.html#comment-2100 CF has an Obstructive component and is a chronic lung disease. It is one of the COPDs. Cystic fibrosis (CF), also called mucoviscidosis, is a hereditary disease that mainly affects the lungs and digestive system, causing progressive disability and early death. Formerly known as cystic fibrosis of the pancreas, this entity has increasingly been labeled simply "cystic fibrosis".[1] Average life expectancy is around 31 years, although improvements in treatments mean a baby born today could expect to live for longer.".[2] Difficulty breathing and insufficient enzyme production in the pancreas are the most common symptoms. Thick mucous production as well as a less competent immune system results in frequent lung infections, which are treated, though not always cured, by oral and intravenous antibiotics and other medications. A multitude of other symptoms, including sinus infections, poor growth, diarrhea, and potential infertility (mostly in males, due to the condition Congenital bilateral absence of the vas deferens) result from the effects of CF on other parts of the body. Often, symptoms of CF appear in infancy and childhood; these include meconium ileus, failure to thrive, and recurrent lung infections. Cystic fibrosis is one of the most common life-shortening, childhood-onset inherited diseases. In the United States, 1 in 3900 children is born with CF.[3] It is most common among Europeans and Ashkenazi Jews; one in twenty-two people of European descent carry one gene for CF, making it the most common genetic disease among such people. Individuals with cystic fibrosis can be diagnosed prior to birth by genetic testing or in early childhood by a sweat test. Newborn screening tests are increasingly common and effective. There is no cure for CF, and most individuals with cystic fibrosis die young—many in their 20s and 30s from lung failure although with many new treatments being introduced the life expectancy of a person with CF is increasing. Ultimately, lung transplantation is often necessary as CF worsens. CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR). The product of this gene is a chloride ion channel important in creating sweat, digestive juices, and mucus. Although most people without CF have two working copies of the CFTR gene, only one is needed to prevent cystic fibrosis. CF develops when neither gene works normally. Therefore, CF is considered an autosomal recessive disease. The name cystic fibrosis refers to the characteristic 'fibrosis' (tissue scarring) and cyst formation within the pancreas, first recognized in the 1930s CF has an Obstructive component and is a chronic lung disease. It is one of the COPDs.
Cystic fibrosis (CF), also called mucoviscidosis, is a hereditary disease that mainly affects the lungs and digestive system, causing progressive disability and early death. Formerly known as cystic fibrosis of the pancreas, this entity has increasingly been labeled simply "cystic fibrosis".[1] Average life expectancy is around 31 years, although improvements in treatments mean a baby born today could expect to live for longer.".[2]

Difficulty breathing and insufficient enzyme production in the pancreas are the most common symptoms. Thick mucous production as well as a less competent immune system results in frequent lung infections, which are treated, though not always cured, by oral and intravenous antibiotics and other medications. A multitude of other symptoms, including sinus infections, poor growth, diarrhea, and potential infertility (mostly in males, due to the condition Congenital bilateral absence of the vas deferens) result from the effects of CF on other parts of the body. Often, symptoms of CF appear in infancy and childhood; these include meconium ileus, failure to thrive, and recurrent lung infections.

Cystic fibrosis is one of the most common life-shortening, childhood-onset inherited diseases. In the United States, 1 in 3900 children is born with CF.[3] It is most common among Europeans and Ashkenazi Jews; one in twenty-two people of European descent carry one gene for CF, making it the most common genetic disease among such people.

Individuals with cystic fibrosis can be diagnosed prior to birth by genetic testing or in early childhood by a sweat test. Newborn screening tests are increasingly common and effective. There is no cure for CF, and most individuals with cystic fibrosis die young—many in their 20s and 30s from lung failure although with many new treatments being introduced the life expectancy of a person with CF is increasing. Ultimately, lung transplantation is often necessary as CF worsens.

CF is caused by a mutation in a gene called the cystic fibrosis transmembrane conductance regulator (CFTR). The product of this gene is a chloride ion channel important in creating sweat, digestive juices, and mucus. Although most people without CF have two working copies of the CFTR gene, only one is needed to prevent cystic fibrosis. CF develops when neither gene works normally. Therefore, CF is considered an autosomal recessive disease. The name cystic fibrosis refers to the characteristic ‘fibrosis’ (tissue scarring) and cyst formation within the pancreas, first recognized in the 1930s

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